CAS: 88642-03-9, 3100-36-5
Aurelione, with CAS numbers 88642-03-9 and 3100-36-5, is a naturally occurring aurone, a class of flavonoids distinguished by their benzofuranone structure. It is a vibrant yellow pigment primarily isolated from plants of the genus Coreopsis, such as Coreopsis grandiflora and Coreopsis maritima. It is typically found as the (Z)-isomer, representing its predominant natural form. Its chemical formula is C15H10O4.
Aurelione is extensively utilized in biochemical and pharmacological research to explore its various biological activities and mechanisms of action. It serves as a valuable reference standard in analytical chemistry for chromatographic and spectrometric methods. Due to its natural origin and color, it is also investigated for its potential as a natural dye or colorant.
Research indicates Aurelione possesses significant antioxidant, anti-inflammatory, and neuroprotective properties, suggesting potential therapeutic applications in fields such as neurodegenerative diseases and inflammatory conditions. In preclinical studies, it has demonstrated anticancer activity and the ability to inhibit enzymes like tyrosinase, making it a candidate for development in cosmetic formulations targeting skin brightening or hyperpigmentation.
Comprehensive safety data for widespread human use of Aurelione are limited, as it is predominantly a research-grade chemical. In experimental settings, natural product isolates like Aurelione are often considered to have relatively low acute toxicity. However, standard laboratory safety protocols should be observed during handling, including the use of personal protective equipment (gloves, eye protection) and ensuring adequate ventilation. It is not intended for ingestion or untested applications.
(Z)-2-(34-Dihydroxybenzylidene)benzofuran-3-one2-(34-Dihydroxybenzylidene)-3(2H)-benzofuranoneAureolCoreopsis aurone AZ-Aurelione[Z]-2-[(34-dihydroxyphenyl)methylidene]-1-benzofuran-3-one
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