Alicate

CAS: 10250-45-0

๐Ÿงช Overview

Alicate, identified by CAS number 10250-45-0, is primarily known as **Diclofensine**. It is a chemical compound classified as a norepinephrine-dopamine reuptake inhibitor (NDRI). Developed by Wander SA (later part of Sandoz/Novartis) in the 1970s, it was investigated as a potential antidepressant but was never commercialized or approved for medical use. Its molecular formula is C18H19Cl2N, with a molar mass of 320.26 g/mol.

โš™๏ธ Uses

Diclofensine (Alicate, CAS 10250-45-0) was developed with the intended use as an antidepressant due to its pharmacological activity as an NDRI. Currently, its primary use is as a research chemical in pharmacology to study the mechanisms of neurotransmitter reuptake and the effects of psychoactive compounds.

๐Ÿญ Applications

Its applications are predominantly in scientific research. It serves as a tool for studying neurochemical pathways, particularly those involving norepinephrine and dopamine, and for investigating the properties of reuptake inhibitors. There are no approved medical, industrial, or commercial applications for Alicate (Diclofensine).

โš ๏ธ Safety Information

As a pharmacologically active compound that was developed as a drug candidate, Alicate (Diclofensine) should be handled with extreme caution. It is not approved for human consumption and may exhibit stimulant-like side effects typical of NDRIs, such as cardiovascular effects, anxiety, or insomnia. Specific detailed toxicity data for humans is not widely available due to its non-commercialized status. Standard laboratory safety practices should be followed, including avoiding ingestion, inhalation, and skin contact, and using appropriate personal protective equipment.

๐Ÿ”ค Synonyms

DiclofensineWD 782Wander 7821-(alpha-(24-Dichlorophenyl)benzyl)piperidine

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